science medium true/false

True or False: SHERLOCK and DETECTR are CRISPR-based diagnostic platforms that detect nucleic acids with high specificity.

  1. True
  2. False

Answer: True

These platforms use Cas13/Cas12 collateral cleavage activated by target binding, coupled with reporter molecules. Enable rapid, portable detection of pathogens (viruses, bacteria), genetic mutations. Potential for point-of-care testing. [[DBT Reports, ICMR Guidelines]]

Topic Biology - CRISPR Diagnostics
Exam Relevance SSC CGL, Railway NTPC, UPSC CAPF

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